* Age
* Repeated use resulting in repetitive strain injury (RSI)
* Injury - strain, sprain and dislocation
* Infection - flu, and viral and bacterial infections through open wounds
* Arthritis
* Rheumatism
* Tendonitis (inflammation of a tendon)
* Psoriasis (a chronic skin disease characterised by scaling and inflammation)
* Gout (one of the most painful rheumatic diseases which results from deposits of needle-like crystals if uric acid in the connective tissue, joint spaces, or both)
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